Establishment of contusion spinal injury animal model using stereotaxic apparatus
نویسندگان
چکیده
منابع مشابه
A contusion model of severe spinal cord injury in rats.
The translational potential of novel treatments should be investigated in severe spinal cord injury (SCI) contusion models. A detailed methodology is described to obtain a consistent model of severe SCI. Use of a stereotactic frame and computer controlled impactor allows for creation of reproducible injury. Hypothermia and urinary tract infection pose significant challenges in the post-operativ...
متن کاملThermostabilized chondroitinase ABC Promotes Neuroprotection after Contusion Spinal Cord Injury
Background: Chondroitinase ABC (cABC), due to its loosening impact on the extracellular matrix scaffold, has been used to enhance regeneration of injured axonal tracts after spinal cord injury (SCI). However, cABC thermal instability at physiological temperature has limited its clinical application. The disaccharide trehalose has been shown to increase the stability of cABC in body temperature....
متن کاملStereotaxic apparatus for frog brain.
Although several studies have been made on the histology of the central nervous system (C S) in anurans (4,5,6, 8, 11,22), frog is still not being used widely by the neurophysiologists. There are obviously many advantages of using this amphibian as an experimental animal such as the easy maintenance in the laboratory throughout the year and the extreme amenability of its C S to the experimental...
متن کاملenhanced neuropathic pain following intraspinaly injection of schwann cells in contusion model of spinal cord injury
enhanced neuropathic pain following intraspinaly injection of schwann cells in contusion model of spinal cord injury pourheydar b [1] *, joghataei mt [2] , najafzadeh n [3] received: 6 nov , 2011 accepted: 20 jan , 2012 abstract background & aims : spinal cord injury (sci) leads to sensorimotor deficits and neuropathic pain (np). cell therapy is a common method for treatment of sc...
متن کاملذخیره در منابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
ژورنال
عنوان ژورنال: IBRO Reports
سال: 2019
ISSN: 2451-8301
DOI: 10.1016/j.ibror.2019.07.931